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2-Chlorobenzothiazole → tert-Butyl 2-((benzo[d]thiazol-2-ylamino)methyl)piperidine-1-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chlorobenzothiazole | HCID 11987 | — |
| 反応物 | tert-Butyl 2-(aminomethyl)piperidine-1-carboxylate | HCID 2756482 | — |
| 溶媒 | Diethyl ether hexane diethyl ether | HCID 22448964 | — |
| 生成物 | tert-Butyl 2-((benzo[d]thiazol-2-ylamino)methyl)piperidine-1-carboxylate | HCID 71631715 | 37.1% |
反応手順
The title compound (1.2 g) after column chromatography (silica gel, 5% diethyl ether/hexane-diethyl ether eluant) was prepared from (RS) 2-aminomethyl-piperidine-1-carboxylic acid tert butyl ester (2.0 g) and 2-chlorobenzothiazole (1.58 g) according to the method of D2.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741329B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-f321b2d5145a4023a4ebe68442df525f |
| 出典メモ | uspto-grants-2010_06 |