Ammonia → HCID 57417080、化合物
反応式
C[O:2][C:3]([C@@H:5]1[CH2:9][C@@H:8]([N:10]([CH3:12])[CH3:11])[CH2:7][NH:6]1)=O.[NH3:13]>CO>[CH3:11][N:10]([CH3:12])[C@H:8]1[CH2:7][NH:6][C@H:5]([C:3]([NH2:13])=[O:2])[CH2:9]1参加物
4
実験手順
A solution of (2S,4R)-4-dimethylamino-pyrrolidine-2-carboxylic acid methyl ester (Stage B.1, 225 mg) and 7 M ammonia in MeOH (7 mL) was stood for 18 h at it in a sealed vessel. Evaporation and trituration with Et2O gave the title compound as a white solid.
後処理
- customEvaporation and trituration with Et2O
出典と根拠
- ORDレコード
- ord-d707340548c94d08856d387734c34a6d
- 出典データセット
- uspto-grants-2013_01
- 特許番号
- US08357707B2
反応ノート
読み込み中…