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Isoquinoline, 1-chloro- → 2-(RS)-(Isoquinolin-1-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isoquinoline, 1-chloro- | HCID 140539 | — |
| 反応物 | tert-Butyl 2-(aminomethyl)piperidine-1-carboxylate | HCID 2756482 | — |
| 生成物 | 2-(RS)-(Isoquinolin-1-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl ester | HCID 86593669 | — |
反応手順
The title compound (0.76 g) was prepared from (RS) 2-aminomethyl-piperidine-1-carboxylic acid tert butyl ester (1.6 ml) and 1-chloroisoquinoline (0.8 g) according to the method used for the preparation of the compound of D8.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741329B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-b00d72bdee644a93bd9c454a819cb045 |
| 出典メモ | uspto-grants-2010_06 |