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tert-Butyl (2S)-2-(aminomethyl)piperidine-1-carboxylate → (S)-2-(1,8-Naphthyridin-2-ylamino)methyl-piperidine-1-carboxylic acid tert butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-Butyl (2S)-2-(aminomethyl)piperidine-1-carboxylate | HCID 1502020 | — |
| 反応物 | 2-Chloro-1,8-naphthyridine | HCID 5152838 | — |
| 生成物 | (S)-2-(1,8-Naphthyridin-2-ylamino)methyl-piperidine-1-carboxylic acid tert butyl ester | HCID 86626012 | 70.8% |
反応手順
The title compound (0.28 g) was prepared from (S)-2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester (0.35 g) and 2-chloro-1,8-naphthyridine (0.19 g) according to the method of D30.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741329B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-f81a3654b4404a418e11bbcfcd345352 |
| 出典メモ | uspto-grants-2010_06 |