化工社化工社 化学情報印刷レポート · 研究参考用
5-Nitro-2-oxindole → 5-Amino-2-oxindole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Nitro-2-oxindole | HCID 230366 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Dimethylacetamide | HCID 31374 | — |
| 生成物 | 5-Amino-2-oxindole | HCID 2773213 | 50.5% |
反応手順
To a solution of 5-nitro-oxindole (25 g) in 120 mL of dimethylacetamide in a Parr bottle was added 10% Pd/C (0.5 g). The mixture was hydrogenated (40 psi H2) for 16 h. The catalyst was removed by filtration and the filtrate was diluted with ether (2 L) to provide 5-amino-oxindole (10.5 g; 50%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741336B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-c74a7df036034b16a9d90a9fbaa46b63 |
| 出典メモ | uspto-grants-2010_06 |