Ethyl Acetate → HCID 22493493、化合物

HRID 1816227ノート

反応式

HRID 1816227 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][NH2:8].[CH3:9][S:10][C:11](SC)=[C:12]([C:16](=O)[CH3:17])[C:13](=[O:15])[CH3:14].C(OCC)(=O)C>[Cl-].[Na+].O>[CH3:17][C:16]1[N:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[N:8]=[C:11]([S:10][CH3:9])[C:12]=1[C:13](=[O:15])[CH3:14]

参加物

5

反応物 3

HCID 8857Ethyl AcetateHCID 786452-HydrazinopyridineHCID 27785933-[bis(methylsulfanyl)methylidene]pentane-2,4-dione

生成物 1

HCID 22493493HCID 22493493、化合物

試薬・触媒・溶媒 1

HCID 57417360Sodium chloride; water溶媒

反応条件

温度
60 °C

実験手順

A mixture of pyridin-2-yl-hydrazine (1.0 equivalent) and 3-(bis-methylsulfanyl-methylene)-pentane-2,4-dione (1.0 equivalent) was stirred at 60° C. overnight. To the reaction mixture was added ethyl acetate and brine, the organic phase was washed by brine twice, dried over magensium sulfate, and filtered. The organic solvent was removed under reduced pressure to provide the title compound.

後処理

  1. washthe organic phase was washed by brine twice
  2. dry with materialdried over magensium sulfate
  3. filtrationfiltered
  4. customThe organic solvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-8fce0c7a6c7e43f681bb815d7cb7e9a5
出典データセット
uspto-grants-2005_04
特許番号
US06884804B2

反応ノート

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