Allylamine → HCID 22493227、化合物

反応式

[CH2:1]([NH:4][C:5](=[O:13])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH2:12])[CH:2]=[CH2:3].[CH2:14]([NH2:17])[CH:15]=C.[C:18]12[C:24](=CC=CC=1)[NH:23]C(=O)OC2=O>>[CH2:1]([NH:4][C:5](=[O:13])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH:12][CH2:15][C:14]1[NH:17][CH2:18][CH2:24][N:23]=1)[CH:2]=[CH2:3]

参加物

反応物 3

HCID 7853Allylamine

HCID 8359Isatoic Anhydride

HCID 2062656N-allyl-2-aminobenzamide

生成物 1

HCID 22493227HCID 22493227、化合物

実験手順

N-Allyl-2-amino benzamide (prepared from allylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give N-allyl-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]benzamide, isolated as the hydrochloride salt.

後処理

customwere reacted

出典と根拠

ORDレコード: ord-23dbf787be854ceebb1efbf99ca9b9cf
出典データセット: uspto-grants-2005_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06884801B1

反応ノート

読み込み中…