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Piperidine → {2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]phenyl}(1-piperidinyl)methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | Isatoic Anhydride | HCID 8359 | — |
| 反応物 | 2-(Piperidine-1-carbonyl)aniline | HCID 558730 | — |
| 生成物 | {2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]phenyl}(1-piperidinyl)methanone | HCID 22493231 | — |
反応手順
1-(2-Aminobenzoyl)piperidine (prepared from piperidine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give {2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]phenyl}(1-piperidinyl)methanone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06884801B1 |
| 出典データセット | uspto-grants-2005_04 |
| ORD ID | ord-c04a3bcf112440099fa5ff8ab35fe904 |
| 出典メモ | uspto-grants-2005_04 |