Aniline → HCID 54077451、化合物
反応式
[NH:1]1[CH2:5][CH2:4][N:3]=[C:2]1[CH2:6][NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[N:14]1[CH2:18][CH2:17][CH2:16][CH2:15]1.F[C:20]1C=CC=C[C:21]=1[N+]([O-])=O.NC1C=CC=CC=1>>[N:14]1([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[NH:7][CH2:6][C:2]2[NH:1][CH2:5][CH2:4][N:3]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:21]=[CH:20]1参加物
4
実験手順
Under conditions similar to those used for the preparation of N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2-(1-pyrrolidinyl)aniline (Example 64), hexamethyleneimine was reacted with 2-fluoronitrobenzene, the nitro group was reduced and the aniline was coupled with CMI to give 2-(1-azepinyl)-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline .
出典と根拠
- ORDレコード
- ord-a862daa34cad486d98f886c27c4f7372
- 出典データセット
- uspto-grants-2005_04
- 特許番号
- US06884801B1
反応ノート
読み込み中…