Hydrazine → HCID 3544473、化合物
反応式
C[N:2](C)[CH:3]=[C:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N+:13]([O-:15])=[O:14])[CH:5]=O.[NH2:17]N>C(O)C>[N+:13]([C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=1[C:4]1[CH:3]=[N:2][NH:17][CH:5]=1)([O-:15])=[O:14]参加物
4
実験手順
3-Dimethylamino-2-(2-nitrophenyl)propenal (Maybridge) in ethanol was treated with hydrazine via syringe and heated to reflux for 16 hours. Concentration in vacuo afforded crude 4-(2-nitrophenyl)pyrazole, which was reduced as in Example 64 and coupled with CMI to give the fumaric acid salt of N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2-(1H-pyrazol-4-yl)aniline.
後処理
- temperatureheated
- temperatureto reflux for 16 hours
- concentrationConcentration in vacuo
出典と根拠
- ORDレコード
- ord-a633342630a0411fb0898a68c189538d
- 出典データセット
- uspto-grants-2005_04
- 特許番号
- US06884801B1
反応ノート
読み込み中…