Acetone → 2-Hydroxy-4-(trifluoromethyl)benzaldehyde
反応式
COC[C:4]1([CH:11]=[CH:10][CH:9]=[C:8]([C:12]([F:15])([F:14])[F:13])[CH2:7]1)C=O.Cl.[OH2:17].C[C:19](C)=[O:20]>>[OH:17][C:4]1[CH:7]=[C:8]([C:12]([F:13])([F:14])[F:15])[CH:9]=[CH:10][C:11]=1[CH:19]=[O:20]参加物
5
実験手順
5.0 g of 1-(methoxymethyl)-3-(trifluoromethyl)benzaldehyde was dissolved in 25 ml acetone, and 22 ml of 6 N hydrochloric acid was added. The mixture was reacted at room temperature for 3 hours, and water was added thereto, followed by extracting with ethyl acetate. The extract was washed with brine, dried over anhydrous magnesium sulfate and the solvent was evapaorated, to give 4.5 g of 2-hydroxy-4-(trifluoromethyl)benzaldehyde as a pale reddish orange oil.
後処理
- customThe mixture was reacted at room temperature for 3 hours
- extractionby extracting with ethyl acetate
- washThe extract was washed with brine
- dry with materialdried over anhydrous magnesium sulfate
出典と根拠
- ORDレコード
- ord-8ed5a0d95cfc4bbaa7ed30a69bdb45f9
- 出典データセット
- uspto-grants-2005_04
- 特許番号
- US06884821B1
反応ノート
読み込み中…