2-Chloro-7,7-dimethyl-7,8-dihydroquinolin-5(6H)-one → 2-Isobutoxy-7,7-dimethyl-7,8-dihydro-6H-quinolin-5-one hydrochloride

HRID 1817818ノート

反応式

HRID 1817818 の反応式
[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[C:8](=[O:12])[CH2:7][C:6]([CH3:14])([CH3:13])[CH2:5][C:4]=2[N:3]=1>C(O)C(C)C>[ClH:1].[CH2:8]([O:12][C:2]1[CH:11]=[CH:10][C:9]2[C:8](=[O:12])[CH2:7][C:6]([CH3:14])([CH3:13])[CH2:5][C:4]=2[N:3]=1)[CH:9]([CH3:10])[CH3:4]

参加物

3

反応物 1

HCID 148125452-Chloro-7,7-dimethyl-7,8-dihydroquinolin-5(6H)-one

生成物 1

HCID 690385882-Isobutoxy-7,7-dimethyl-7,8-dihydro-6H-quinolin-5-one hydrochloride収率 35%

試薬・触媒・溶媒 1

HCID 6560Isobutanol溶媒

実験手順

In analogy to the procedure described in Example 9, 2-chloro-7,7-dimethyl-7,8-dihydro-6H-quinolin-5-one was treated with iso-butyl alcohol to give the title compound in 35% yield.

出典と根拠

ORDレコード
ord-31f381eb02a646eaaefb6d89be1b36f9
出典データセット
uspto-grants-2009_10
特許番号
US07598384B2

反応ノート

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