化工社化工社 化学情報印刷レポート · 研究参考用
Phenylboronic Acid → 2-butyl-1-isobutyl-7-phenyl-1H-imidazo[4,5-c]quinolin-4-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenylboronic Acid | HCID 66827 | — |
| 反応物 | 7-Bromo-2-butyl-1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine | HCID 68817944 | — |
| 生成物 | 2-butyl-1-isobutyl-7-phenyl-1H-imidazo[4,5-c]quinolin-4-amine | HCID 21984072 | — |
反応手順
7-Bromo-2-butyl-1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine and benzeneboronic acid were coupled according to the general procedure described in Part J of Example 1. Purification by chromatography on silica gel (20% acetone in toluene to 60% acetone in toluene gradient) afforded 2-butyl-1-isobutyl-7-phenyl-1H-imidazo[4,5-c]quinolin-4-amine as a white solid, m.p.>250° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07598382B2 |
| 出典データセット | uspto-grants-2009_10 |
| ORD ID | ord-ca3a8cf6e815424bb66ee541d883b74f |
| 出典メモ | uspto-grants-2009_10 |