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Hydrochloric Acid → 3-Benzyl-5-methyl-7-piperazin-1-yl-benzofuran-2-carboxylic acid amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 4-(3-Benzyl-2-carbamoyl-5-methyl-benzofuran-7-yl)-piperazine-1-carboxylic acid tert-butyl ester | HCID 59344904 | — |
| 生成物 | 3-Benzyl-5-methyl-7-piperazin-1-yl-benzofuran-2-carboxylic acid amide | HCID 24953422 | — |
反応手順
4-(3-Benzyl-2-carbamoyl-5-methyl-benzofuran-7-yl)-piperazine-1-carboxylic acid tert-butyl ester was deprotected using ethanolic HCl, following the procedure of step 4 of Example 2, to provide 3-benzyl-5-methyl-7-piperazin-1-yl-benzofuran-2-carboxylic acid amide as a hydrochloride salt, (M+H)+ 350.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741326B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-97a9fd022b854579aaf220708ba361e1 |
| 出典メモ | uspto-grants-2010_06 |