Ammonia → 1-(5-Amino-2-hydroxyphenyl)ethanone
反応式
[C:1]([C:4]1[CH:5]=[C:6]([NH:11]C(=O)C)[CH:7]=[CH:8][C:9]=1[OH:10])(=[O:3])[CH3:2].Cl.N>>[NH2:11][C:6]1[CH:7]=[CH:8][C:9]([OH:10])=[C:4]([C:1](=[O:3])[CH3:2])[CH:5]=1参加物
4
実験手順
A suspension of N-(3-acetyl-4-hydroxy-phenyl)-acetamide (1.029 g, 5.3 mmol) in 15% HCl (1.5 ml, 6.2 mmol, 1.2 equ) was heated to reflux for 40 minutes, then cooled and neutralised with 10% aqueous ammonia. The precipitated solid was collected by filtration as 1-(5-amino-2-hydroxy-phenyl)-ethanone (0.677 g, 84%) a green solid.
後処理
- temperaturewas heated
- temperatureto reflux for 40 minutes
- filtrationThe precipitated solid was collected by filtration as 1-(5-amino-2-hydroxy-phenyl)-ethanone (0.677 g, 84%) a green solid
出典と根拠
- ORDレコード
- ord-2ed52949da7949a6977a868312158493
- 出典データセット
- uspto-grants-2009_10
- 特許番号
- US07601754B2
反応ノート
読み込み中…