4-Bromobenzohydrazide → 2-(4-Bromophenyl)-1,3,4-oxadiazole

HRID 1820742

反応式

HRID 1820742 の反応式
[Br:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[CH:4][CH:3]=1.[CH:12](OCC)(OCC)OCC>>[Br:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]2[O:7][CH:12]=[N:9][N:8]=2)=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 222194-BromobenzohydrazideHCID 31214Ethyl orthoformate

生成物 1

HCID 7151202-(4-Bromophenyl)-1,3,4-oxadiazole

実験手順

12.3 mmol of 4-bromo-benzoic acid hydrazide were dissolved in 26 ml of triethyl orthoformate. The reaction mixture was stirred overnight at 140°, evaporated and the residue crystallized from ethanol to give the title compound as a colorless solid. MS (m/e): 225.0 (MH+, 100%)

後処理

  1. customevaporated
  2. customthe residue crystallized from ethanol

出典と根拠

ORDレコード
ord-79989d43b7124d63ba0f90eb321aa375
出典データセット
uspto-grants-2009_10
特許番号
US07605163B2

関連ノート

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