4-Nitrobenzaldehyde → HCID 178477495、化合物

HRID 1822482ノート

反応式

HRID 1822482 の反応式
O=Cc1ccc([N+](=O)[O-])cc1.CCSC(=O)C(OCc1ccccc1)C(=O)O>NCc1ccccc1.O=C(O)C(F)(F)F.CN(C)c1ccncc1.CN(C)C=O>CCSC(=O)/C(=C/c1ccc([N+](=O)[O-])cc1)OCc1ccccc1

参加物

6

反応物 2

HCID 5414-NitrobenzaldehydeHCID 178477513HCID 178477513、化合物

生成物 1

HCID 178477495HCID 178477495、化合物収率 71%

試薬・触媒・溶媒 3

HCID 142844-(Dimethylamino)pyridine試薬HCID 12484433Benzenemethanamine, trifluoroacetate触媒HCID 6228Dimethylformamide溶媒

反応条件

温度
25 °C

後処理

  1. temperatureThe product mixture was cooled to 25 °C.
  2. filtrationFiltered through a pad of celite · Organic 相を保持
  3. wash"The celite was washed with ethyl acetate (3 x 1 mL)."
  4. concentrationThe filtrate was concentrated under reduced pressure
  5. additionA 0.07 M stock solution of the internal standard ethylene carbonate (0.70 mL in CDCl3) was added.

出典と根拠

ORDレコード
ord-cea0e0e42a174a3fa38538e7667e472a
出典データセット
Bayesian optimization of 5 decarboxylative olefination reactions

反応ノート

読み込み中…