2-Chlorobenzenesulfonamide → 2-chloro-N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-benzenesulfonamide

関与物質

役割	名称	HCID	仕込み量
反応物	2-Chlorobenzenesulfonamide	HCID 81410	—
反応物	3-[4-(Z)-(1,2-diphenylbut-1-enyl)phenyl]-acrylic acid	HCID 3036152	—
生成物	2-chloro-N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-benzenesulfonamide	HCID 69316648	—

反応手順

Prepared by coupling 1a and 2-chlorobenzenesulfonamide in accordance with Procedure 1, Method B described hereinabove. Yield (19%); 1H NMR (d6-DMSO) δ 12.56 (s, 1H), 8.09 (d, J=7.7 Hz, 1H), 7.69–7.53 (m, 3H), 7.39–7.08 (m, 13H), 6.85 (d, J=8.1 Hz, 2H), 6.47 (d, J=15.8 Hz, 1H), 2.36 (q, J=7.3 Hz, 2H), 0.82 (t, J=7.3 Hz, 3H); APcI m/z: 528 (M+H+).

情報源と証拠

DOI	10.6084/m9.figshare.5104873.v1
特許番号	US07045540B2
出典データセット	uspto-grants-2006_05
ORD ID	ord-14d8e45322ad4978ae1b4712a6b422a9
出典メモ	uspto-grants-2006_05