2-Bromo-4-chlorophenol → 7-Bromo-5-chloro-1-benzofuran

HRID 1824917ノート

反応式

HRID 1824917 の反応式
BrC1C=C(Cl)C=CC=1O.C(O[CH:13](OCC)[CH2:14][O:15][C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][C:17]=1[Br:23])C>>[Cl:22][C:19]1[CH:18]=[C:17]([Br:23])[C:16]2[O:15][CH:14]=[CH:13][C:21]=2[CH:20]=1

参加物

3

反応物 2

HCID 696702-Bromo-4-chlorophenolHCID 221447972-(2-Bromo-4-chlorophenoxy)-acetaldehyde diethyl acetal

生成物 1

HCID 221447207-Bromo-5-chloro-1-benzofuran

実験手順

Beginning with 25 gm (120.5 mMol) 2-bromo-4-chlorophenol, 41.16 gm crude 2-(2-bromo-4-chlorophenoxy)-acetaldehyde diethyl acetal was prepared essentially as described in Preparation IV. A sample of this crude material was subjected to silica gel chromatography to provide an analytical sample.

後処理

  1. customwas prepared essentially
  2. customto provide an analytical sample

出典と根拠

ORDレコード
ord-f3b736e892984b3cae31ec04bafada74
出典データセット
uspto-grants-2006_05
特許番号
US07045545B1

反応ノート

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