2-Hydrazinoethanol → Ethyl 1-(2-hydroxyethyl)-5-methylpyrazole-3-carboxylate
反応式
[OH:1][CH2:2][CH2:3][NH:4][NH2:5].O=[C:7]([CH2:13][C:14](=O)[CH3:15])[C:8]([O:10][CH2:11][CH3:12])=[O:9].C(N1C(CC)=CC(C(O)=O)=N1)C>C(Cl)Cl>[OH:1][CH2:2][CH2:3][N:4]1[C:14]([CH3:15])=[CH:13][C:7]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[N:5]1参加物
5
実験手順
The title compound was prepared from hydroxyethyl hydrazine (3.64 g, 50 mM) and ethyl 2,4-dioxovalerate (8.5 g, 50 mM) as described in Example 1 Preparation 1 as a colourless oil (9.39 g, 95%); νmax (CH2Cl2) 1700 cm−1; δH(CDCl3) 1.39 (3H, t, J7 Hz), 2.40 (3H, s), 2.98 (2H, t, J7 Hz), 4.33-4.48 (4H, m), and 6.39 (1H, s); E.I. m/e 198 (95%).
出典と根拠
- ORDレコード
- ord-d031f63a2e17420490bb4b84c816b0cf
- 出典データセット
- uspto-grants-2006_05
- 特許番号
- US07045619B2
反応ノート
読み込み中…