Hydrochloric Acid → N-[3-(dimethylamino)propyl]acrylamide acrylamide N-dodecylacrylamide

HRID 1825696

反応式

HRID 1825696 の反応式
[CH3:1][N:2]([CH3:11])[CH2:3][CH2:4][CH2:5][NH:6][C:7](=[O:10])[CH:8]=[CH2:9].[C:12]([NH2:16])(=[O:15])[CH:13]=[CH2:14].[CH2:17]([NH:29][C:30](=[O:33])[CH:31]=[CH2:32])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].Cl.Cl.N(C(C(=N)N)(C)C)=NC(C(=N)N)(C)C.Cl>O.C(O)C.C(O)(C)C>[CH3:11][N:2]([CH3:1])[CH2:3][CH2:4][CH2:5][NH:6][C:7](=[O:10])[CH:8]=[CH2:9].[C:12]([NH2:16])(=[O:15])[CH:13]=[CH2:14].[CH2:17]([NH:29][C:30](=[O:33])[CH:31]=[CH2:32])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

参加物

9

反応物 5

HCID 313Hydrochloric AcidHCID 6579AcrylamideHCID 73929N-DodecylacrylamideHCID 763442,2'-Azobis(2-methylpropanimidamide) dihydrochlorideHCID 77452N,N-Dimethylaminopropyl acrylamide

生成物 1

HCID 86757470N-[3-(dimethylamino)propyl]acrylamide acrylamide N-dodecylacrylamide

試薬・触媒・溶媒 3

HCID 702Ethanol溶媒HCID 962Water溶媒HCID 3776Isopropanol溶媒

実験手順

A solution of N-[3-(dimethylamino)propyl]acrylamide (22.5 g), acrylamide (2.7 g), and N-dodecylacrylamide (2.3 g) in deionized water (30 mL) and ethanol (30 mL) was heated to 60° C. under a nitrogen atmosphere. When the solution reached 60° C., 2,2′-azobis(2-amidinopropane) dihydrochloride (1.4 g of a 20 percent aqueous solution) was added. Heating was continued for 18 hours under a nitrogen atmosphere. After cooling to room temperature, the reaction solution was dissolved in isopropanol (150 mL), and concentrated HCl (29.2 g) was added with stirring. The solution was decanted from the precipitated polymer. The polymer was suspended in isopropanol (500 mL), stirred for at least 15 minutes, and allowed to settle. After decanting, the polymer was similarly washed an additional 3 times with isopropanol. The washed polymer was dried in a forced-air oven at 70° C. to afford 34.7 g.

後処理

  1. customreached 60° C.
  2. temperatureHeating
  3. customThe solution was decanted from the precipitated polymer
  4. stirringstirred for at least 15 minutes
  5. customAfter decanting
  6. washthe polymer was similarly washed an additional 3 times with isopropanol
  7. customThe washed polymer was dried in a forced-air oven at 70° C.
  8. customto afford 34.7 g

出典と根拠

ORDレコード
ord-c9005f8284f1478082968a4a0a4d3634
出典データセット
uspto-grants-2006_05
特許番号
US07048917B1

関連ノート

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