Methanol → 4-{4-[2-(2,2,6,6-Tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-phenyl}-butan-2-ol

反応式

[BH4-:29].[CH3:1][C:2]1([CH3:28])[NH:3][C:4]([CH3:26])([CH3:27])[CH2:5][CH:6]([NH:8][c:9]2[n:10][cH:11][cH:12][c:13](-[c:15]3[cH:16][cH:17][c:18]([CH2:21][CH2:22][C:23]([CH3:24])=[O:25])[cH:19][cH:20]3)[n:14]2)[CH2:7]1.[CH3:31][OH:32].[Na+:30]>>[CH3:1][C:2]1([CH3:28])[NH:3][C:4]([CH3:26])([CH3:27])[CH2:5][CH:6]([NH:8][c:9]2[n:10][cH:11][cH:12][c:13](-[c:15]3[cH:16][cH:17][c:18]([CH2:21][CH2:22][CH:23]([CH3:24])[OH:25])[cH:19][cH:20]3)[n:14]2)[CH2:7]1