Skatole → 1,7-Dimethyl-1H-indole

反応式

[CH3:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][CH:8]=[CH:7]2.[CH3:11]C1C2C(=CC=CC=2)NC=1>>[CH3:11][N:9]1[C:10]2[C:6](=[CH:5][CH:4]=[CH:3][C:2]=2[CH3:1])[CH:7]=[CH:8]1

参加物

反応物 2

HCID 6736Skatole

HCID 702757-Methylindole

生成物 1

HCID 5893901,7-Dimethyl-1H-indole収率 90%

実験手順

According to the procedure of Preparation 13 (a), except substituting 7-methylindole for the 3-methylindole, the title compound (1.95 g, 90%) was obtained as a light-colored oil: MS (ES) m/e 146.2 (M+H)+.

出典と根拠

ORDレコード: ord-d31ddab030d84c639376e37cd06f3781
出典データセット: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07741339B2

反応ノート

読み込み中…