Methyl 4-(aminomethyl)benzoate → Methyl 4-(acetamidomethyl)benzoate
反応式
[NH2:1][CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1.C(C1(N[C:34]([CH:36](NC(N2CCOCC2)=O)CC(C)(C)C)=[O:35])CC(C2C=CC=CC=2)NC(C2C=CC=CC=2)C1)#N.C(C1(NC(C(NC(N2CCOCC2)=O)CC2CCCCC2)=O)CCN(C)CC1C)#N>C(O)(=O)C>[CH3:10][O:9][C:7](=[O:8])[C:6]1[CH:5]=[CH:4][C:3]([CH2:2][NH:1][C:34](=[O:35])[CH3:36])=[CH:12][CH:11]=1参加物
5
反応物 3
生成物 1
試薬・触媒・溶媒 1
実験手順
Methyl-4-(acetylamino-methyl)-benzoate was prepared from acetic acid and methyl 4-(aminomethyl)benzoate using a method analogous to that of Example 1-part (d). The crude N-acyl ester was saponified using a method analogous to that of Example 1-part (c). The crude product was used without further purification.
後処理
- customThe crude product was used without further purification
出典と根拠
- ORDレコード
- ord-cdb95c2952dc4cf2ac6968de6e52a013
- 出典データセット
- uspto-grants-2006_06
- 特許番号
- US07056915B2
反応ノート
読み込み中…