Cesium acetate → Acetic Acid 5-phenyl-benzoxazol-2-ylmethyl Ester
反応式
Br[CH2:2][C:3]1[O:4][C:5]2[CH:11]=[CH:10][C:9]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[CH:8][C:6]=2[N:7]=1.[C:18]([O-:21])(=[O:20])[CH3:19].[Cs+]>CN(C=O)C.C(OCC)(=O)C>[C:12]1([C:9]2[CH:10]=[CH:11][C:5]3[O:4][C:3]([CH2:2][O:21][C:18](=[O:20])[CH3:19])=[N:7][C:6]=3[CH:8]=2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1参加物
5
実験手順
A mixture of 2-bromomethyl-5-phenyl-benzoxazole 49 (440 mg, 1.53 mmol) and cesium acetate (585 mg, 3.06 mmol) in 5 ml DMF was stirred overnight at room temperature. The reaction mixture was diluted with ethyl acetate, washed with brine, dried, filtered and concentrated to yield acetic acid 5-phenyl-benzoxazole-2-ylmethyl ester 50.
後処理
- washwashed with brine
- customdried
- filtrationfiltered
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-2e188c415892487789c4070142030e02
- 出典データセット
- uspto-grants-2006_06
- 特許番号
- US07056903B2
反応ノート
読み込み中…