Glycolic Acid → (Propionyloxy)acetic acid
反応式
[C:1](Cl)(=[O:4])[CH2:2][CH3:3].[OH:6][CH2:7][C:8]([OH:10])=[O:9]>>[C:1]([O:6][CH2:7][C:8]([OH:10])=[O:9])(=[O:4])[CH2:2][CH3:3]参加物
3
実験手順
a solution consisting of propionyl chloride (64.7 g, 0.7 mol) and hydroxyacetic acid (19.0 g, 0.25 mol) is heated at 40° C., until the hydroxyacetic acid has completely dissolved. The excess propionyl chloride is then distilled off and 35.6 g of crude product containing 82% of (propionyloxy)acetic acid is obtained as a colorless liquid. The crude product can be used in the subsequent reaction without further purification.
後処理
- dissolutionhas completely dissolved
- distillationThe excess propionyl chloride is then distilled off
- addition35.6 g of crude product containing 82% of (propionyloxy)acetic acid
- customis obtained as a colorless liquid
出典と根拠
- ORDレコード
- ord-507d3a629a8e4d0f8d464525d6f98f48
- 出典データセット
- uspto-grants-2006_06
- 特許番号
- US07064102B2
反応ノート
読み込み中…