3-Formyl-2-methylindole → 6-methoxy-1-methyl-3-(methylaminomethyl)-1H-indole
反応式
[CH3:1][O:2][C:3]1[CH:11]=[C:10]2[C:6]([C:7]([CH:13]=O)=[CH:8][N:9]2[CH3:12])=[CH:5][CH:4]=1.C[C:16]1[NH:17]C2C(C=1C=O)=CC=CC=2>>[CH3:1][O:2][C:3]1[CH:11]=[C:10]2[C:6]([C:7]([CH2:13][NH:17][CH3:16])=[CH:8][N:9]2[CH3:12])=[CH:5][CH:4]=1参加物
3
実験手順
According to the procedure of Preparation 12, except substituting 6-methoxy-1-methyl-1H-indole-3-carboxaldehyde for the 2-methylindole-3-carboxaldehyde, the title compound (2.1 g, 87%) was obtained as an oil: MS (ES) m/e 205.2 (M+H)+.
後処理
- customAccording to the procedure of Preparation 12
出典と根拠
- ORDレコード
- ord-1c8a60f402cc4e689b7230c732359e90
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07741339B2
反応ノート
読み込み中…