4-Morpholinecarbonyl chloride → HCID 69517789、化合物
反応式
[OH:1][N:2]1[CH:6]=[C:5]([Br:7])[CH:4]=[N:3]1.[N:8]1([C:14](Cl)=[O:15])[CH2:13][CH2:12][O:11][CH2:10][CH2:9]1>>[Br:7][C:5]1[CH:4]=[N:3][N:2]([O:1][C:14]([N:8]2[CH2:13][CH2:12][O:11][CH2:10][CH2:9]2)=[O:15])[CH:6]=1参加物
3
実験手順
The title compound was prepared from 1-hydroxy-4-bromopyrazole and 4-morpholine carbonyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (85%, crystals).
後処理
- customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (85%, crystals)
出典と根拠
- ORDレコード
- ord-76a106a1d63c47d195f4b02953999479
- 出典データセット
- uspto-grants-2006_06
- 特許番号
- US07067517B2
反応ノート
読み込み中…