Sodium Dithionite → 3-Amino-6-chloro-4H-chromen-4-one
反応式
S(S([O-])=O)([O-])=O.[Na+].[Na+].[N+:9]([C:12]1[C:17](=[O:18])[C:16]2[CH:19]=[C:20]([Cl:23])[CH:21]=[CH:22][C:15]=2[O:14][CH:13]=1)([O-])=O>O.C(O)C>[NH2:9][C:12]1[C:17](=[O:18])[C:16]2[CH:19]=[C:20]([Cl:23])[CH:21]=[CH:22][C:15]=2[O:14][CH:13]=1参加物
5
実験手順
Sodium dithionite (20 g, 0.115 mole) was added to a suspension of 3-nitro-6-chloro-4H-1-benzopyran-4-one (7.0 g, 0.037 mole) in water (80 ml) and absolute ethanol (30 ml). The reaction mixture was refluxed under nitrogen for 3 hrs., concentrated at reduced pressure and filtered. The solids were washed with water and recrystallized from acetone to give yellow crystals (5.44 g, 90%), m.p. 184°-186°.
後処理
- temperatureThe reaction mixture was refluxed under nitrogen for 3 hrs
- concentration, concentrated at reduced pressure
- filtrationfiltered
- washThe solids were washed with water
- customrecrystallized from acetone
出典と根拠
- ORDレコード
- ord-1d3353080c4b484d93395414dcfae57d
- 出典データセット
- uspto-grants-1978_01
- 特許番号
- US04066655
反応ノート
読み込み中…