HCID 12736922、化合物 → HCID 12736925、化合物
反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:14][C:13]3[C:12](=[O:15])[C:11]([C:16]([O:18]CC)=[O:17])=[CH:10][NH:9][C:8]=3[C:7](=[O:21])[C:6]=2[CH:22]=1>Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:14][C:13]3[C:12](=[O:15])[C:11]([C:16]([OH:18])=[O:17])=[CH:10][NH:9][C:8]=3[C:7](=[O:21])[C:6]=2[CH:22]=1参加物
3
実験手順
A suspension of ethyl 8-chloro-4,10-dihydro-4,10-dioxo-1H-1-benzopyrano[3,2-b]pyridine-3-carboxylate (3.0 g, 0.0094 mole) in 6N hydrochloric acid (100 ml ) was refluxed under nitrogen for 15 hrs., cooled and filtered. The residue was washed with water and with acetone. Recrystallization from DMF gave white crystals (2.4 g, 87%), m.p. 325°-327°.
後処理
- temperaturewas refluxed under nitrogen for 15 hrs
- temperature, cooled
- filtrationfiltered
- washThe residue was washed with water and with acetone
- customRecrystallization from DMF
出典と根拠
- ORDレコード
- ord-15d3af4e6b18494ebd91db1be938a377
- 出典データセット
- uspto-grants-1978_01
- 特許番号
- US04066655
反応ノート
読み込み中…