Di-tert.-butyl 2-(4-acetoxynonyl)-2-[4-(ethoxycarbonylmethoxy)-butyl]-malonate → Ethyl 5-carboxy-9-acetoxytetradecyloxyacetate

HRID 1833456ノート

反応式

HRID 1833456 の反応式
C(OC(CCCCC)CCCC(CCCCCCC(OCC)=O)(C(OC(C)(C)C)=O)C(OC(C)(C)C)=O)(=O)C.[C:40]([O:43][CH:44]([CH2:74][CH2:75][CH2:76][CH2:77][CH3:78])[CH2:45][CH2:46][CH2:47][C:48]([CH2:63][CH2:64][CH2:65][CH2:66][O:67][CH2:68][C:69]([O:71][CH2:72][CH3:73])=[O:70])(C(OC(C)(C)C)=O)[C:49]([O:51]C(C)(C)C)=[O:50])(=[O:42])[CH3:41]>>[C:49]([CH:48]([CH2:47][CH2:46][CH2:45][CH:44]([O:43][C:40](=[O:42])[CH3:41])[CH2:74][CH2:75][CH2:76][CH2:77][CH3:78])[CH2:63][CH2:64][CH2:65][CH2:66][O:67][CH2:68][C:69]([O:71][CH2:72][CH3:73])=[O:70])([OH:51])=[O:50]

参加物

3

反応物 2

HCID 21317616Di-tert.-butyl 2-(4-acetoxynonyl)-2-[4-(ethoxycarbonylmethoxy)-butyl]-malonateHCID 21317623Di-tert.-butyl 2-(4-acetoxynonyl)-2-(6-ethoxycarbonylhexyl)-malonate

生成物 1

HCID 21317571Ethyl 5-carboxy-9-acetoxytetradecyloxyacetate

実験手順

This compound is prepared essentially by the method described in Example 1, Step D except that the di-tert.-butyl 2-(4-acetoxynonyl)-2-(6-ethoxycarbonylhexyl)-malonate of the example is replaced by di-tert.-butyl 2-(4-acetoxynonyl)-2-[4-(ethoxycarbonylmethoxy)-butyl]-malonate. The title compound is purified by column chromatography on silica gel.

後処理

  1. customThis compound is prepared essentially by the method
  2. customThe title compound is purified by column chromatography on silica gel

出典と根拠

ORDレコード
ord-ca73ebd545974b919e8ee68bbe610ef4
出典データセット
uspto-grants-1978_01
特許番号
US04066675

反応ノート

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