関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Malonic Acid | HCID 867 | — |
| 反応物 | Benzaldehyde, 4-hexyl- | HCID 170813 | — |
| 触媒 | Piperidine | HCID 8082 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | p-n-Hexylcinnamic acid | HCID 53878923 | — |
反応手順
9.4 G. of p-n-hexylbenzaldehyde in 5 ml. of absolute pyridine are treated with 5.15 g. of malonic acid and 5 drops of piperidine. The mixture is then heated at 100° C. for 11 hours, subsequently poured on to cold aqueous hydrochloric acid and extracted with ether. The p-n-hexylcinnamic acid obtained after recrystallization of the crude product from hexane/ether has a melting point of 107°-109° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04066570 |
|---|
| 出典データセット | uspto-grants-1978_01 |
|---|
| ORD ID | ord-511137de192940c4a23533203fb55e02 |
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| 出典メモ | uspto-grants-1978_01 |
|---|
