HCID 21388034、化合物 → HCID 21388032、化合物
反応式
[C:1]([N:5]1[CH2:9][CH:8]([CH2:10][O:11][C:12]2[C:21]3[C:16](=[CH:17][CH:18]=[C:19]([Cl:22])[CH:20]=3)[C:15]([CH3:23])=[CH:14][N:13]=2)[O:7]C1C1C=CC=CC=1)([CH3:4])([CH3:3])[CH3:2]>Cl>[OH:7][CH:8]([CH2:9][NH:5][C:1]([CH3:4])([CH3:3])[CH3:2])[CH2:10][O:11][C:12]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([Cl:22])[CH:20]=2)[C:15]([CH3:23])=[CH:14][N:13]=1参加物
3
実験手順
1 g of 1-(3-tert.-Butyl-2-phenyl-5-oxazolidinyl-methoxy)-7-chloro-4-methylisoquinoline is heated to 80° in 10 ml of 1N hydrochloric acid for 10 minutes. The reaction mixture is extracted with ether. The ethereal phase is discarded and the aqueous phase worked up to yield the title compound in free base form. M.p. 116°-117°.
後処理
- extractionThe reaction mixture is extracted with ether
出典と根拠
- ORDレコード
- ord-745197a7ef254b54a06f2dcd24e6ae9a
- 出典データセット
- uspto-grants-1978_01
- 特許番号
- US04067873
反応ノート
読み込み中…