Isothiazole → N-[2-(3-isothiazolylmethylthio)ethyl)-N'-methyl-N"-nitroguanidine

HRID 1834623

反応式

HRID 1834623 の反応式
S1C=C[CH:3]=N1.CSC(=N)N[N+]([O-])=O.[S:14]1[CH:18]=[CH:17][C:16]([CH2:19][S:20][CH2:21][CH2:22][NH:23][C:24]([NH:26][N+:27]([O-:29])=[O:28])=[NH:25])=[N:15]1.CNC(=N[N+]([O-])=O)SC>>[S:14]1[CH:18]=[CH:17][C:16]([CH2:19][S:20][CH2:21][CH2:22][NH:23][C:24]([NH:25][CH3:3])=[N:26][N+:27]([O-:29])=[O:28])=[N:15]1

参加物

5

反応物 4

HCID 67515IsothiazoleHCID 135927615N-Nitro-S-methylisothioureaHCID 1362270171,2-Dimethyl-3-nitroisothioureaHCID 178512219HCID 178512219、化合物

生成物 1

HCID 136353517N-[2-(3-isothiazolylmethylthio)ethyl)-N'-methyl-N"-nitroguanidine

実験手順

Reacting 3-[2-aminoethyl)thiomethyl]isothiazole with S-methyl-N-nitroisothiourea by the procedure of Example 2(ii) gives N-[2-(3-isothiazolylmethylthio)ethyl]-N'-nitroguanidine and reaction of the same starting material with N,S-dimethyl-N'-nitroisothiourea by the procedure of Example 2(iii) gives N-[2-(3-isothiazolylmethylthio)ethyl]-N'-methyl-N"-nitroguanidine.

後処理

  1. customgives

出典と根拠

ORDレコード
ord-0203fad603ef4a168fc0ecfbd0ca1857
出典データセット
uspto-grants-1978_01
特許番号
US04070475

関連ノート

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