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5alpha-Androstane-3beta,17beta-diol → 19-Methoxy-3beta-triphenylsiloxy-5alpha-androstan-17-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5alpha-Androstane-3beta,17beta-diol | HCID 242332 | — |
| 反応物 | 3beta,17beta-Dihydroxy-5alpha-androstan-19-one | HCID 21626207 | — |
| 反応物 | 19-Hydroxy-3beta-triphenylsiloxy-5alpha-androstan-17-one | HCID 22801524 | — |
| 反応物 | 1beta-Methyl-5alpha-androstane-3beta,17beta,19-triol 3,17-diacetate | HCID 70614636 | — |
| 生成物 | 19-Methoxy-3beta-triphenylsiloxy-5alpha-androstan-17-one | HCID 22801525 | — |
| 生成物 | 17alpha-Methyl-17beta,19-dimethoxy-5alpha-androstane | HCID 70614924 | — |
| 生成物 | 19-Methoxy-1beta-methyl-5alpha-androstane-3beta,17beta-diol diacetate | HCID 86735437 | — |
| 生成物 | 3beta,17beta-Dimethoxy-5alpha-androstan-19-one | HCID 88801553 | — |
反応手順
Substituting 1β-methyl-5α-androstane-3β,17β,19-triol 3,17-diacetate, 17α-methyl-5α-androstane-17β,19-diol, 19-hydroxy-3β-triphenylsiloxy-5α-androstan-17-one and 3β,17β-dihydroxy-5α-androstan-19-one for the 1β-methyl-19-2'-tetrahydropyranyloxy)-5α-androstane-3β,17β-diol above results in the preparation of 19-methoxy-1β-methyl-5α-androstane-3β,17β-diol diacetate, 17α-methyl-17β,19-dimethoxy-5α-androstane, 19-methoxy-3β-triphenylsiloxy-5α-androstan-17-one and 3β,17β-dimethoxy-5α-androstan-19-one, respectively.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04071625 |
| 出典データセット | uspto-grants-1978_01 |
| ORD ID | ord-5bca20f9fe4f44d59fc34d938ecfbcaa |
| 出典メモ | uspto-grants-1978_01 |