Potassium Carbonate → HCID 69901207、化合物
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[CH2:7][C:8]#[N:9])([O-:3])=[O:2].O.[C:14]([OH:18])(=[O:17])[CH:15]=O.C(=O)([O-])[O-].[K+:23].[K+]>CO>[K+:23].[C:8]([C:7]([C:6]1[CH:10]=[CH:11][CH:12]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1)=[CH:15][C:14]([O-:18])=[O:17])#[N:9]参加物
5
実験手順
A suspension of 3-nitrobenzyl cyanide (1.62 g), glyoxylic acid monohydrate (1.38 g) and potassium carbonate (3.59 g) in methanol (20 ml) was stirred for 5 hours. The precipitate was collected by filtration, washed with dichloromethane and dried. The precipitate was suspended in water and stirred for an hour. The insoluble material was collected by filtration and dried to give 3-cyano-3-(3-nitro-phenyl)-acrylic acid potassium salt (2.18 g, 85.2%).
後処理
- filtrationThe precipitate was collected by filtration
- washwashed with dichloromethane
- customdried
- stirringstirred for an hour
- filtrationThe insoluble material was collected by filtration
- customdried
出典と根拠
- ORDレコード
- ord-33e6f6ad422b4b8f8e8527c7ea30be2f
- 出典データセット
- uspto-grants-2004_08
- 特許番号
- US06770667B1
反応ノート
読み込み中…