5-(Toluene-4-sulfonyl)-thiazolidine-2,4-dione → 5-Pent-4-ynyl-5-(toluene-4-sulfonyl)-thiazolidine-2,4-dione

反応式

I[CH2:2][CH2:3][CH2:4][C:5]#[CH:6].[C:7]1([CH3:23])[CH:12]=[CH:11][C:10]([S:13]([CH:16]2[S:20][C:19](=[O:21])[NH:18][C:17]2=[O:22])(=[O:15])=[O:14])=[CH:9][CH:8]=1>>[CH2:2]([C:16]1([S:13]([C:10]2[CH:11]=[CH:12][C:7]([CH3:23])=[CH:8][CH:9]=2)(=[O:14])=[O:15])[S:20][C:19](=[O:21])[NH:18][C:17]1=[O:22])[CH2:3][CH2:4][C:5]#[CH:6]

参加物

反応物 2

HCID 107545835-(Toluene-4-sulfonyl)-thiazolidine-2,4-dione

HCID 110197205-Iodo-1-pentyne

生成物 1

HCID 226780015-Pent-4-ynyl-5-(toluene-4-sulfonyl)-thiazolidine-2,4-dione

実験手順

In the manner of Example 100 above, 5-iodo-1-pentyne is created with 5-(toluene-4-sulfonyl)-thiazolidine-2,4-dione to give the title compound, mp 226° C., THEORY: C,53.4, H, 4.48, N, 4.15 FOUND: C, 53.3, H, 4.58, N, 4.13.

出典と根拠

ORDレコード: ord-1af79ca61ba040faad820c17a13c14f2
出典データセット: uspto-grants-2004_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06784184B2

反応ノート

読み込み中…