Hydrochloric Acid → HCID 22678561、化合物

HRID 1837688ノート

反応式

HRID 1837688 の反応式
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][C:16]2[S:17][CH:18]=[CH:19][C:20]=2[S:21]([CH3:24])(=[O:23])=[O:22])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:25]>C(OCC)(=O)C>[ClH:25].[CH3:24][S:21]([C:20]1[CH:19]=[CH:18][S:17][C:16]=1[CH2:15][CH2:14][CH:11]1[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1)(=[O:22])=[O:23]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 226783201-Tert-butoxycarbonyl-4-[2-(3-methylsulfonyl-2-thienyl)ethyl]piperidine

生成物 1

HCID 22678561HCID 22678561、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒2 回

実験手順

11.1 g of 1-tert-butoxycarbonyl-4-[2-(3-methylsulfonyl-2-thienyl)ethyl]piperidine was dissolved in 100 ml of ethyl acetate, 100 ml of an ethyl acetate solution of 4N hydrochloric acid was added thereto, and the mixture was further stirred at room temperature for 2 hours. The resulting crystals were collected by filtration, washed with ethyl acetate, and air-dried, to give 7.92 g of the title compound as colorless crystals.

後処理

  1. filtrationThe resulting crystals were collected by filtration
  2. washwashed with ethyl acetate
  3. customair-dried

出典と根拠

ORDレコード
ord-e6d41132ce9540478b98fcd511322d1d
出典データセット
uspto-grants-2004_08
特許番号
US06784192B2

反応ノート

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