(Z)-Benzaldehyde oxime → Methyl 3-phenylisoxazole-4-carboxylate
反応式
F[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]([C:13]([O:15][CH3:16])=[O:14])=[CH:11][O:10][N:9]=2)=[CH:4][CH:3]=1.C(=NO)C1C=CC=CC=1>>[C:5]1([C:8]2[C:12]([C:13]([O:15][CH3:16])=[O:14])=[CH:11][O:10][N:9]=2)[CH:4]=[CH:3][CH:2]=[CH:7][CH:6]=1参加物
3
実験手順
This compound was synthesised following the procedure described for Compound 8C but using benzaldoxime instead of 4-fluorobenzaldoxime as a starting material. The crude was purified twice by flash chromatography (toluene-acetone 96:4 followed by toluene) to give the title compound as an oil (35%).
後処理
- customThis compound was synthesised
- customThe crude was purified twice by flash chromatography (toluene-acetone 96:4 followed by toluene)
出典と根拠
- ORDレコード
- ord-9e46f34d1f4a4772bc239ff417afeb61
- 出典データセット
- uspto-grants-2004_01
- 特許番号
- US06680319B2
反応ノート
読み込み中…