Water → HCID 2222571、化合物
反応式
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[CH3:11][O:12][C:13](=[O:18])[C@H:14]([CH2:16][OH:17])[NH2:15].O.C(=O)(O)[O-].[Na+]>C(OCC)(=O)C>[CH3:11][O:12][C:13](=[O:18])[C@H:14]([CH2:16][OH:17])[NH:15][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
6
実験手順
A solution of benzoyl chloride (17 g) in ethyl acetate (40 ml) is added dropwise, with stirring, in an ice-cold mixture of L-serine methyl ester, hydrochloride (15.5 g), water (100 ml), sodium bicarbonate (21.8 g), and ethyl acetate (100 ml). After stirring for 2 hours, the organic phase is separated, dried over sodium sulfate, and evaporated to give crystalline N-benzoyl-L-serine methyl ester (22.0 g).
後処理
- customthe organic phase is separated
- dry with materialdried over sodium sulfate
- customevaporated
出典と根拠
- ORDレコード
- ord-83ee98549dc3492085213156d5ba2f87
- 出典データセット
- uspto-grants-2004_01
- 特許番号
- US06680387B2
反応ノート
読み込み中…