化工社化工社 化学情報印刷レポート · 研究参考用
Quinuclidine, 3-amino-, dihydrochloride → (Rs)-n-(1-azabicyclo[2.2.2]oct-3-yl)[e-3-(2-trifluoromethylphenyl)propenamide]
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Quinuclidine, 3-amino-, dihydrochloride | HCID 197853 | — |
| 反応物 | 2-(Trifluoromethyl)cinnamic acid, (E)- | HCID 719625 | — |
| 生成物 | (Rs)-n-(1-azabicyclo[2.2.2]oct-3-yl)[e-3-(2-trifluoromethylphenyl)propenamide] | HCID 9945116 | — |
反応手順
Prepared as a free base by a method analogous to that described in Example 1 from racemic 1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-3-(2-trifluoromethylphenyl)propenoic acid; MS (ES+) 325 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06683090B1 |
| 出典データセット | uspto-grants-2004_01 |
| ORD ID | ord-20d1366df0bf4007a0db4970cb2f3893 |
| 出典メモ | uspto-grants-2004_01 |