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HRID 1840941作成日:2026年10月26日

Tert-butyl 4-(benzyloxy)benzoate → tert-Butyl 4-hydroxybenzoate

https://huagongshe.com/reaction/1840941

反応式

関与物質

役割名称HCID仕込み量
反応物Tert-butyl 4-(benzyloxy)benzoateHCID 53864121—
触媒PalladiumHCID 23938—
溶媒EthanolHCID 702—
生成物tert-Butyl 4-hydroxybenzoateHCID 11764095%

反応手順

0.36 g of 10% palladium on activated carbon were added to a solution of 1.2 g (4.3 mmol) of 4-benzyloxy-benzoic acid tert-butyl ester in 45 mL of ethanol and this mixture was hydrogenated at 20 psi for 3 hours. After filtering over celite and removing the solvent under reduced pressure 0.79 g (95% yield) of 4-hydroxy-benzoic acid tert-butyl ester were obtained.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06683096B2
出典データセットuspto-grants-2004_01
ORD IDord-088307d29382438e849941b901475049
出典メモuspto-grants-2004_01