化工社化工社 化学情報印刷レポート · 研究参考用
Tert-butyl 4-(benzyloxy)benzoate → tert-Butyl 4-hydroxybenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tert-butyl 4-(benzyloxy)benzoate | HCID 53864121 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | tert-Butyl 4-hydroxybenzoate | HCID 117640 | 95% |
反応手順
0.36 g of 10% palladium on activated carbon were added to a solution of 1.2 g (4.3 mmol) of 4-benzyloxy-benzoic acid tert-butyl ester in 45 mL of ethanol and this mixture was hydrogenated at 20 psi for 3 hours. After filtering over celite and removing the solvent under reduced pressure 0.79 g (95% yield) of 4-hydroxy-benzoic acid tert-butyl ester were obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06683096B2 |
| 出典データセット | uspto-grants-2004_01 |
| ORD ID | ord-088307d29382438e849941b901475049 |
| 出典メモ | uspto-grants-2004_01 |