Cyclopropanecarbonitrile → Cyclopropyl 2-amino-3,5-dimethylphenyl ketone

反応式

[NH2:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([CH3:9])=[CH:4][C:3]=1[C:10](=[O:12])[CH3:11].[CH:13]1(C#N)C[CH2:14]1>>[NH2:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([CH3:9])=[CH:4][C:3]=1[C:10]([CH:11]1[CH2:14][CH2:13]1)=[O:12]

参加物

反応物 2

HCID 79637Cyclopropanecarbonitrile

HCID 105831361-(2-Amino-3,5-dimethylphenyl)ethan-1-one

生成物 1

HCID 23445385Cyclopropyl 2-amino-3,5-dimethylphenyl ketone

実験手順

Cyclopropyl 2-amino-3,5-dimethylphenyl ketone was synthesized in the same fashion as for 2′-amino-3′,5′-dimethylacetophenone (Example 39) except that cyclopropyl cyanide was used instead of acetonitrile.

出典と根拠

ORDレコード: ord-30c3ff94369443f7a47708ff6e7abda5
出典データセット: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06683103B2

反応ノート

読み込み中…