1-(2-Ethylphenyl)piperazine → 1-[(5,6-Dimethyl-2-methoxypyrazin-3-yl)aminothiocarbonyl]-4-(2-ethylphenyl)piperazine

HRID 1841464

反応式

HRID 1841464 の反応式
[CH3:1][C:2]1[N:3]=[C:4]([NH:11][C:12](=[S:20])OC2C=CC=CC=2)[C:5]([O:9][CH3:10])=[N:6][C:7]=1[CH3:8].[CH2:21]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[N:29]1[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]1)[CH3:22]>>[CH3:1][C:2]1[N:3]=[C:4]([NH:11][C:12]([N:32]2[CH2:33][CH2:34][N:29]([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=3[CH2:21][CH3:22])[CH2:30][CH2:31]2)=[S:20])[C:5]([O:9][CH3:10])=[N:6][C:7]=1[CH3:8]

参加物

3

反応物 2

HCID 27364601-(2-Ethylphenyl)piperazineHCID 54547361Phenyl N-(5,6-dimethyl-2-methoxypyrazin-3-yl)thiocarbamate

生成物 1

HCID 544426201-[(5,6-Dimethyl-2-methoxypyrazin-3-yl)aminothiocarbonyl]-4-(2-ethylphenyl)piperazine収率 64%

実験手順

Phenyl N-(5,6-dimethyl-2-methoxypyrazin-3-yl)thiocarbamate and 1-(2-ethylphenyl)piperazine were reacted by the same way with the example 28 to obtain the titled compound.

出典と根拠

ORDレコード
ord-6695442acaef4797bd249dde45a00be4
出典データセット
uspto-grants-2004_01
特許番号
US06683184B2

関連ノート

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