1-(3,8-Diaza-bicyclo[3.2.1]oct-3-yl)-ethanone hydrochloride → 1-{8-[(S)-4-(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-3,8-diaza-bicyclo[3.2.1]oct-3-yl}-ethanone
反応式
C(OC(N1CCN([CH2:14][C:15]2[CH:20]=[CH:19][C:18]([C@@H:21]3[O:30][C:25]4=[N:26][CH:27]=[CH:28][CH:29]=[C:24]4[O:23][CH2:22]3)=[CH:17][CH:16]=2)CC1)=O)(C)(C)C.Cl.[CH:32]12[NH:39][CH:36]([CH2:37][CH2:38]1)[CH2:35][N:34]([C:40](=[O:42])[CH3:41])[CH2:33]2>>[O:23]1[C:24]2[C:25](=[N:26][CH:27]=[CH:28][CH:29]=2)[O:30][C@@H:21]([C:18]2[CH:19]=[CH:20][C:15]([CH2:14][N:39]3[CH:32]4[CH2:38][CH2:37][CH:36]3[CH2:35][N:34]([C:40](=[O:42])[CH3:41])[CH2:33]4)=[CH:16][CH:17]=2)[CH2:22]1参加物
3
反応物 2
生成物 1
実験手順
Compound 271 is synthesized from Intermediate C and Intermediate U according to General Method H. (LC/MS method 16: ES+ m/z 380.5 [M+H]+, Rt=2.52 min)
出典と根拠
- ORDレコード
- ord-c7651fc4c9314d918a828b11b6f6211e