化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 2,4,5-Trifluoro-3-methoxybenzoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 2,4,5-Trifluoro-3-methoxybenzoic acid | HCID 2733970 | — |
| 生成物 | 2,4,5-Trifluoro-3-methoxybenzoyl chloride | HCID 2775281 | — |
反応手順
A mixture of 2,4,5-trifluoro-3-methoxybenzoic acid (154 mg, 0.75 mmol) and thionyl chloride (8 mL) is refluxed for 4 h. Excess thionyl chloride is removed in vacuo, and the remaining residue is used directly in the next synthetic step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08946422B2 |
| 出典データセット | uspto-grants-2015_02 |
| ORD ID | ord-d8bd22cc7a604f0ea2f8c25d160b063b |
| 出典メモ | uspto-grants-2015_02 |