反応式
[CH3:1][N:2]1[C:10]2[C:9](=[O:11])[NH:8][C:7](=[O:12])[NH:6][C:5]=2[N:4]=[CH:3]1.N1C(=O)C2NC=NC=2N[C:14]1=O>>[N:8]1([C:9](=[O:11])[C:10]2[N:2]([CH3:1])[CH:3]=[N:4][C:5]=2[NH:6][C:7]1=[O:12])[CH3:14]参加物
3
実験手順
N-Demethylation of paraxanthine by Ndm also resulted in production of formaldehyde. After 90 minutes of incubation, 338.5±7.7 μM of paraxanthine was N-demethylated by 7.4 units of Ndm and approximately 540.6±20.9 μM of formaldehyde was produced (FIG. 5). 7-Methylxanthine (126.9±6.40 μM) and xanthine (193.7±4.0 μM) were the N-demethylated products. Tallying up all the products formed from paraxanthine, it was determined that approximately one molecule of formaldehyde was produced per methyl group removed.
出典と根拠
- ORDレコード
- ord-c320960723a94b7f8905c64cf6c546c5
- 出典データセット
- uspto-grants-2015_02
- 特許番号
- US08951752B2
関連ノート
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