4-Methoxy-2-nitroaniline → [(4-Methoxy-2-nitrophenyl)imino]ethyl acetate
反応式
[CH3:1][O:2][C:3]1[CH:9]=[CH:8][C:6]([NH2:7])=[C:5]([N+:10]([O-:12])=[O:11])[CH:4]=1.[C:13]([O:17][CH2:18][CH3:19])(=[O:16])[CH:14]=O.C1(C)C=CC=CC=1>C1(C)C=CC=CC=1>[C:13]([O:17][CH2:18][CH:19]=[N:7][C:6]1[CH:8]=[CH:9][C:3]([O:2][CH3:1])=[CH:4][C:5]=1[N+:10]([O-:12])=[O:11])(=[O:16])[CH3:14]参加物
4
実験手順
A mixture of 4-methoxy-2-nitroaniline (1.68 g, 10.0 mmol), ethyl glyoxylate/toluene solution (50 wt %, 1.98 ml, 10.0 mmol) and toluene (20 ml) was heated under reflux under a nitrogen gas atmosphere for 17 hours while removing water using a Dean-Stark apparatus. The solvent was removed under reduced pressure to yield [(4-methoxy-2-nitrophenyl)imino]ethyl acetate crude product.
後処理
- temperaturewas heated
- temperatureunder reflux under a nitrogen gas atmosphere for 17 hours
- customwhile removing water using a Dean-Stark apparatus
- customThe solvent was removed under reduced pressure
出典と根拠
- ORDレコード
- ord-cffe90dd2da54221bfbcd4ac685f7f72
- 出典データセット
- uspto-grants-2015_02
- 特許番号
- US08952010B2
反応ノート
読み込み中…