Cyclopropylboronic acid → Tert-butyl 4-(adamantan-1-ylmethoxy)-5-cyclobutyl-2-fluorobenzoate

反応式

Cl[C:2]1[C:3]([O:16][CH2:17][C:18]2([C:24]#N)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]2)=[CH:4][C:5]([F:15])=[C:6]([CH:14]=1)[C:7]([O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[O:8].C12(CO[C:38]3[C:50](Cl)=[CH:49][C:41](C(OC(C)(C)C)=O)=C(F)C=3)CC3CC(CC(C3)C1)C2.[CH:53]1(B(O)O)[CH2:55][CH2:54]1.C1(B(O)O)CCC1.F[B-](F)(F)F.C1(P(C2CCCCC2)C2CCCCC2)CCCCC1.C1(P(C2CCCCC2)C2C=CC=CC=2C2C(OC(C)C)=CC=CC=2OC(C)C)CCCCC1>>[C:18]12([CH2:17][O:16][C:3]3[C:2]([CH:41]4[CH2:49][CH2:50][CH2:38]4)=[CH:14][C:6]([C:7]([O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[O:8])=[C:5]([F:15])[CH:4]=3)[CH2:23][CH:22]3[CH2:54][CH:53]([CH2:55][CH:20]([CH2:21]3)[CH2:19]1)[CH2:24]2