化工社化工社 化学情報印刷レポート · 研究参考用
Methyl 2-acetamidoacrylate → Methyl 6-methylisoquinoline-3-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 2-acetamidoacrylate | HCID 98644 | — |
| 反応物 | 2-Bromo-4-methylbenzaldehyde | HCID 4645292 | — |
| 生成物 | Methyl 6-methylisoquinoline-3-carboxylate | HCID 22243644 | 50% |
反応手順
methyl 6-methyl-isoquinoline-3-carboxylate was prepared using the procedure described in example 12A: 2-bromo-4-methylbenzaldehyde was reacted with methyl 2-acetamidoacrylate at 110° C. for 18 hours to yield methyl 6-methyl-isoquinoline-3-carboxylate (50%) as brown solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08962627B2 |
| 出典データセット | uspto-grants-2015_02 |
| ORD ID | ord-ed8c84d3d8f7478eac387d95047051c1 |
| 出典メモ | uspto-grants-2015_02 |